Barcoded synthetic lethal screening to identify drug targets
CA 2398690 A1 · Owner: Brenner, Charles M. · Inventors: Brenner, Charles M.; Shoemaker, Daniel D.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to methods of using synthetic lethal screening techniques to identify drug targets. The methods of the present invention use "barcoded" libraries of cells, where the library consists of a collection of different mutant clones, each mutant clone bearing a knock-out mutation of a different gene. Each mutant clone has a unique DNA identifier tag or , "barcode", to allow for quick and convenient identification of the clone and its mutation. The use of such a library allows for rapid quantitative, sensitive and simple identification of genes which interact with a mutated target gene. So identified genes are promising targets for drug screening.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 18, 2001. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended January 18, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 18, 2023.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.