Circularly permutated, interaction-activated proteins
CA 2397162 A1 · Owner: Panorama Research, Inc. · Inventors: Balint, Robert F.; Her, Jeng-Horng
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Interaction-activated circularly permutated proteins are disclosed that depend for their functional reassembly into the parent protein on the interaction of heterologous polypeptides or other molecules which have been genetically or chemically conjugated to the break-point termini of engineered enzymes. Additionally, methods are provided for identifying circularly permutated marker proteins that will optimally reassemble into a functional parent protein, and which are dependent on the association of heterologous interactor domains. The invention is exemplified by circular permutations of a Class A .beta.-lactamase (TEM-1 of E. coli). Circularly permutated marker proteins comprising …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 16, 2001. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended January 16, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 16, 2023.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.