Microbial 9a-hydroxylation of steroids
CA 2396879 A1 · Owner: Hessels, Gerda · Inventors: Van Der Geize, Robert; Hessels, Gerda; Dijkhuizen, Lubbert
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A method is described to construct genetically modified strains of steroid degrading micro-organisms wherein multiple genes involved in steroid nucleus degradation are inactivated, such as steroid dehydrogenase genes. Examples for such genes are kstD1 and kstD2: strains with multiple inactivated steroid degrading enzyme genes can be used in the accumulation of steroid intermediates with a high yield. A preferred accumulation product is 9.alpha.hydroxy-4-androstene-3,17-dione.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed October 17, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended October 17, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by October 17, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.