Intrabodies with defined framework that is stable in a reducing environment and applications thereof
CA 2396534 C · Owner: Escher, Dominik · Inventors: Auf Der Maur, Adrian; Escher, Dominik; Barberis, Alcide
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A method for the isolation of CDRs in a defined framework that is stable and soluble in reducing environment is described as well as thus obtainable scFv. Starting from such scFv with defined framework a scFv library can be generated wherein the framework is conserved while at least one complementary determining region (CDR) is randomized. Such library e.g. in yeast cells, is , suitable for screening for antibody/CDR-interactions or for screening for antibodies.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 18, 2000 and granted October 2, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended December 18, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 18, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.