Yeast-based process for production of l-pac
CA 2394265 A1 · Owner: Polychip Pharmaceuticals Pty. Ltd. · Inventors: Trewhella, Maurice Arthur; Smallridge, Andrew John; Wilkinson, Kylie Anne
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention provides a method of synthesis of a substituted or unsubstituted carbinol compound, comprising the steps of subjecting the corresponding substituted or unsubstituted aromatic aldehyde to acyloin condensation mediated by yeast in the presence of either (a) a supercritical fluid or (b) a liquefied gas, and recovering the carbinol compound. Preferably the yeast is Saccharomyces cerevisiae. In a particularly preferred embodiment the aromatic aldehyde is benzaldehyde and the carbinol is phenylacetylcarbinol according , to the reaction (I): in which the benzaldehyde the pyruvic acid, or both may , optionally be substituted.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 13, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended December 13, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 13, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.