Methods and compositions for modulating er-stress-induced cholesterol accumulation
CA 2391875 A1 · Owner: Hamilton Civic Hospitals Research Development Inc. · Inventors: Werstuck, Geoff; Austin, Richard Carl
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides methods for preventing the accumulation of cholesterol/triglycerides within mammalian cells. The present methods are based upon the surprising discovery that ER stress in a cell leads to cholesterol/triglyceride accumulation within the cell which , cholesterol/triglyceride accumulation is often a causative factor in the development of any of a number of conditions or diseases such as , atherosclerosis. The ER stress can be the result of any of a variety of causes, including homocysteine, viral infection and hypoxia. Accordingly, counteracting the progression or the severity of ER stress can be used to inhibit the accumulation of cholesterol/triglycerides …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed November 16, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended November 16, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by November 16, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.