Methods for screening candidate drugs that disrupt mif and jab1 interaction, mif and jab1 complex, antibodies and uses thereof
CA 2391392 C · Owner: Brunner, Herwig · Inventors: Kleemann, Robert; Mischke, Ralf; Bernhagen, Jurgen
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A method for screening candidate drugs is disclosed. The method tests whether the candidate drug disrupts an interaction between MIF (macrophage migration inhibitory factor) and Jab1 (c-Jun activation domain binding protein). The method comprises the step of detecting in a MIF and Jab1 system, in the absence of the candidate drug an interaction between , MIF and Jabi and comparing the detected interaction to an interaction detected in the MIF and Jabi system in the presence of the candidate drug. The method is not practiced on the human body.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed November 2, 2000 and granted July 17, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended November 2, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by November 2, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.