Delivery of proteins across polar epithelial cell layers
CA 2389302 C · Owner: The Government Of The United States Of America, Represented By The Secretary Of The Department Of Health And Human Services · Inventors: Fitzgerald, David J.; Mckee, Marian; Mrsny, Randall J.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
This invention provides bioactive conjugates. The bioactive conjugates include: (1) a cell recognition moiety that binds to .alpha.2 macroglobulin receptor .alpha.2-MR and (2) a bioactive moiety which: (a) has a biological activity (b) does not function , solely as an immunogen to invoke an immune response and (c) does not have ADP ribosylating activity. The bioactive conjugates of this invention are useful in methods of transporting the bioactive moiety across a polar epithelial membrane. Thus this invention , provides methods for parenteral administration of proteins without injection.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed October 18, 2000 and granted March 15, 2011. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended October 18, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by October 18, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.