Method for preparing chiral ester
CA 2387950 A1 · Owner: Park, Jai Wook · Inventors: Kim, Mahn-Joo; Jung, Hyun Min; Koh, Jeong Hwan
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to a process for preparing a chiral ester expressed in formula (100) by mixing and reacting: a ketone of formula (4); a ruthenium complex selected from the group consisting of compounds (1 2 and 3) , expressed in formula (1) to (3) to activate hydrogenation of said ketone to a racemic alcohol and racemization of said racemic alcohol; a lipase to acylate selectively one of enantiomers of said racemic alcohol; a hydride donor group to supply a hydride group to said ruthenium complex; and an acyl donor group to supply acyl group to said lipase. In formula (1) wherein Y1 Y2, Y3, Y4, Y5, Y6, Y7, Y8, Y9, Y10, Y11 and Y12 are independentlya hydrogen atom or C1- …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed October 18, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended October 18, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by October 18, 2022.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.