Methods of treating vascular diseases characterized by nitric oxide insufficiency
CA 2386954 C · Owner: Loscalzo, Joseph · Inventors: Worcel, Manuel; Loscalzo, Joseph; Loberg, Michael D.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides methods of treating and/or preventing vascular diseases where nitric oxide insufficiency is a contributing factor by administering a therapeutically effective amount of at least one antioxidant or a pharmaceutically acceptable salt thereof and at least one of isosorbide , dinitrate and isosorbide mononitrate and, optionally, at least one nitrosated angiotensin-converting enzyme inhibitor nitrosated beta-adrenegic blocker, nitrosated calcium channel blocker nitrosated endothelin antagonist, nitrosated angioetnsin II receptor antagonist nitrosated renin inhibitor, and/or at least one compound used to treat cardiovascular diseases. The antioxidant is …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed October 27, 2000 and granted December 13, 2011. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended October 27, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by October 27, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.