Viral replicons and viruses dependent on inducing agents
CA 2386530 A1 · Owner: Academisch Ziekenhuis Bij De Universiteit Van Amsterdam · Inventors: Berkhout, Benjamin; Verhoef, Koenraad Dirk
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
In one aspect the invention provides an inducible viral replicon comprising , at least one inducible repressor and/or activator and all viral sequences , which are essential for replication under direct or indirect control of said inducible repressor and/or activator. Said inducible repressor and/or activator may comprise a Tet operon. A replicon of the invention may be used to produce a virus, for instance an attenuated HIV virus which can be induced , to replicate by the presence of doxycycline or a functional analog thereof. Said replicon and/or said produced virus is suitable for the preparation of a vaccine, for instance for the prophylaxis of AIDS. A replicon of the invention …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 8, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended September 8, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 8, 2022.
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Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.