System for monitoring the expression and/or location of transgenes
CA 2381941 A1 · Owner: Mayo Foundation For Medical Education And Research · Inventors: Peng, Kah-Whye; Morris, John; Russell, Stephen James
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A novel strategy for monitoring both the expression and/or localization of a transgene in a mammal is disclosed. A marker peptide and/or sodium iodide symporter is genetically fused to either the N-terminus or C-terminus of the product of a transgene through a linker peptide which bears the recognition sequence of a host cell protease. Expression of the transgene results in release of the marker peptide into extracellular body fluid of the mammal in proportion to the amount of transgene product. The level of the released marker peptide serves as an indicator of the level of transgene expression. Expression of the transgene confers the activity of the sodium iodide symporter (NIS) …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed August 17, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended August 17, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by August 17, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.