Process for preparing optically active 2-¬6-(hydroxy-methyl)-1,3-dioxan-4-yl acetic acid derivatives
CA 2380997 A1 · Owner: Inoue, Kenji · Inventors: Yasohara, Yoshihiko; Inoue, Kenji; Ueyama, Noboru
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A process for preparing optically active 2-6-(hydroxy-methyl)-1,3-dioxan-4ylacetic acid derivatives which comprises reacting an enolate prepared by reacting an acetic acid ester derivative with a base or a zero-valent metal with (S)-.beta.-hydroxy-.gamma.-butyrolactone at a temperature of -30~C or above to thereby obtain a dihydroxyoxohexanoic acid derivative treating this , derivative with an acylating agent in the presence of a base to thereby obtain a monoacylated derivative of dihydroxyoxohexanoic acid reducing the , monoacylated derivative with a microorganism into a monoacylated derivative of trihydroxyhexanoic acid, treating the resulting derivative with an acetalforming …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed June 5, 2001. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended June 5, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by June 5, 2023.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.