In vivo induction for enhanced function of isolated hepatocytes
CA 2378893 C · Owner: Gregory, Paul G. · Inventors: Gregory, Paul G.; Dimilla, Paul A.; Sullivan, Susan J.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention features a liver cell culture comprising hepatocytes that have increased detoxification enzyme activity when isolated from a liver of a donor that had been administered at least one induction agent prior isolation of hepatocyte cells. The induced hepatocytes are used in a bioreactor and cultured to produce hepatocyte cell products or metabolize toxins added to the culture. The bioreactor is, or is an integral part of a liver assist device , used to treat a patient in need of liver assist.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 24, 2000 and granted August 30, 2011. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended July 24, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 24, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.