Stable factor viii compositions
CA 2378751 C · Owner: Sandberg, Helena · Inventors: Mikaelsson, Marianne; Sandberg, Helena
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to a pharmaceutical composition comprising Factor VIII and the divalent metal ions Zn2+ and Cu2+ optionally in the , presence of Ca2+ ions and/or Mn2+ ions wherein said Factor VIII is stable , without the addition of albumin. The invention also relates to a method for the production of recombinant Factor VIII from mammalian cells carrying the gene therefor, comprising culturing said mammalian cells in medium free of plasma-derived protein and supplemented with divalent metal ions including , Cu2+ and Zn2+, and optionally in the presence of Ca2+ and Mn2+ ions.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 7, 2000 and granted November 6, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended July 7, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 7, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.