Purification and stabilization of peptide and protein pharmaceutical agents
CA 2377204 C · Owner: Steiner, Solomon S. · Inventors: Woods, Rodney J.; Steiner, Solomon S.; Sulner, Joseph W.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Methods are provided for purifying peptides and proteins by incorporating the peptide or protein into a diketopiperazine or competitive complexing agent to facilitate removal of one or more impurities i.e. undesirable components, from the peptide or protein. In a preferred embodiment a peptide, such as , insulin, containing one or more impurities e.g. zinc ions, is entrapped in , diketopiperazine to form a precipitate of peptide/diketopiperazine/impurity which is then washed with a solvent for the impurity to be removed which is a , nonsolvent for the diketopiperazine and a nonsolvent for the peptide. Formulations and methods also are provided for the improved transport of active agents …
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed June 29, 2000 and granted January 20, 2015. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended June 29, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by June 29, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.