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Hyaluronidase from the hirudinaria manillensis, isolation, purification and recombinant method of production

CA 2376467 A1 · Owner: Kordowicz, Maria · Inventors: Pacuszka, Tadeusz; Gardas, Andrzej; Kordowicz, Maria

CIPO record

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Abstract From the Canadian patent

The present invention relates to the isolation purification and , characterization of a hyaluronidase which derives from the tropical leech <i>Hirudinaria manillensis</i>. Therefore according to this invention, the , enzyme was called "<u>manillase</u>". The invention is furthermore concerned with the recombinant method of production of manillase which includes the disclosure of DNA and amino acid sequences as well as of expression vectors and host systems. Finally, the invention relates to the use of manillase for therapeutic purposes, for example, for the treatment of myocardial diseases thrombotic events and tumors.

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed June 6, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended June 6, 2020.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by June 6, 2022.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledJune 6, 2000
GrantedNo grant recorded
Term endedJune 6, 2020
Patent numberCA 2376467 A1
Classification (IPC)C12N15/52 +2 more

Timeline

Timeline From CIPO dates

2001200320052007200920112013201520172019Application filedJune 6, 2000Term endedJune 6, 2020

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.