Spatially-encoded analyte detection

Abstract From the Canadian patent

A flow-through microchannel (e.g. capillary) biosensor is described for the detection of multiple, different analytes (e.g. nucleic acids proteins, sugars, etc.) targets in a sample by binding them to "complementary" binding partners (e.g. complementary nucleic acids ligands, antibodies, etc.). The , binding partners are immobilized in different sections of a microchannel (e.g. a fused silica capillary). After fabrication of the biosensor a sample is , flushed through the capillary and any target analyte(s) contained within the sample are bound to the immobilized binding partner(s) on the microchannel wall forming bound complexes. Finally, the bound complexes are simultaneously …