Protein localization assays for toxicity and antidotes thereto
CA 2375155 A1 · Owner: Kauvar, Lawrence M. · Inventors: Kauvar, Lawrence M.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Intracellular translocation of proteins particularly protein kinase C (PKC) , isoenzymes provides a surrogate test system for determining toxicity of candidate compounds. The profile of translocation with respect to at least one and preferably two or more signal transduction proteins can be correlated with that of known toxins. In addition, databases of such profiles with respect to toxins of various types provide a useful set of standards for evaluating toxicity of candidate compounds. Moreover to the extent that a toxin's , profile mimics that found in a diseased state the toxin can be used to , construct screens for compounds alleviating the disease.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed June 14, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended June 14, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by June 14, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.