A process for the preparation of .beta.-lactam derivatives
CA 2374686 A1 · Owner: Cabri, Walter · Inventors: Cabri, Walter; Siviero, Enrico; Terrassan, Daniele Mario
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A process for the preparation of Cefuroxime acid (I) which comprises the , following steps: (1) Extraction of deacetyl 7-glutaryl ACA (II) aqueous solution at acid pH with organic solvents (for example according to the procedures disclosed in US 5,801,241); (2) drying the resulting solution while preventing lactonization of the intermediate; (3) carbamoylation of the hydroxymethyl group at the 3- position by reaction with chlorosulfonyl isocyanate or similar products; (7) extraction of the carbamoyl derivative from step 3 with water at neutral pH; (8) enzymatic hydrolysis of the amide at the 7- position of the cephalosporanic ring with glutaryl acylase; (6) acylation of the amino …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 16, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 16, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 16, 2022.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.