Methods for display of heterodimeric proteins on filamentous phage using pvii and pix, compositions, vectors and combinatorial libraries
CA 2374505 C · Owner: The Scripps Research Institute · Inventors: Janda, Kim D.; Lerner, Richard A.; Gao, Changshou
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention describes the display of exogenous polypeptides on filamentous phage using a fusion between the exogenous polypeptide and phage pVII or pIX proteins. In particular, phage particles and phagemid vectors are described for expression and display of heterodimeric proteins such as antibody Fv heterodimers in combinatorial libraries and uses thereof.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 24, 2000 and granted October 25, 2011. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended May 24, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 24, 2022.
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Timeline
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.