Novel cyanine and indocyanine dye bioconjugates for biomedical applications
CA 2373475 C · Owner: Rajagopalan, Raghavan · Inventors: Bugaj, Joseph Edward; Rajagopalan, Raghavan; Achilefu, Samuel
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Dye-peptide conjugates useful for diagnostic imaging and therapy are disclosed. The dye-peptide conjugates include several cyanine dyes with a variety of bis- and tetrakis (carboxylic acid) homologues. The small size of the compounds allows more favorable delivery to tumor cells as compared to larger molecular weight imaging agents. The various dyes are useful over the range of 350-1300 nm, the exact range being dependent upon the particular dye. Use of dimethylsulfoxide helps to maintain the fluorescence of the compounds. The molecules of the invention are useful for diagnostic imaging and therapy in endoscopic applications for the detection of tumors and other abnormalities and …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 26, 2000 and granted October 23, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended April 26, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 26, 2022.
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.