Gene therapy using tgf-.beta.
CA 2373045 C · Owner: Noh, Moon Jong · Inventors: Kang, Kyoung Ae; Noh, Moon Jong; Lee, Kwan Hee
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The subject invention is related to a cell-mediated gene therapy treatment for orthopedic disease using a member belonging to the transforming growth factor- .beta. (TGF-.beta.) superfamily. TGF-.beta. gene therapy as a new treatment method for degenerative arthritis is demonstrated. After transfection of TGF- .beta. cDNA expression vectors into fibroblasts (NIH 3T3-TGF-.beta.1) the , cells were injected into rabbit achilles tendon and knee joints with artificially-made cartilage defects. Intratendinous injections were performed to determine the optimal concentration for in vivo expression. Partially defected cartilage model was made to simulate degenerative arthritis of the knee …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 3, 2000 and granted July 26, 2016. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended May 3, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 3, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.