1-(p-thienylbenzyl)-imidazoles as angiotensin-(1-7) receptor agonists, method for the production and the utilization thereof and pharmaceutical preparations containing said compounds
CA 2373010 A1 · Owner: Heitsch, Holger · Inventors: Wiemer, Gabriele; Heitsch, Holger
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to novel 1-(p-thienylbenzyl)-imidazoles of formula (I) wherein radicals R(1)-R(6), X and Y have the meaning cited in the description. Said compounds are potent agonists of angiotensin-(1-7) receptors. As a result of the production and release of vasodilating antithrombotic and , cardioprotective messengers such as cyclic 3',5'-guanosine monophosphate (cGMP) and nitrogen monoxide (NO) associated with the stimulation of said receptors in the endothelial cells, said compounds represent valuable medicaments in the treatment and prophylaxis of hypertension heart , hypertrophy, heart failure, coronary heart diseases such as Angina Pectoris myocardial infarct, vascular …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 29, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended April 29, 2020.
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.