Antimicrobial theta defensins and methods of using same
CA 2372821 C · Owner: Selsted, Michael E. · Inventors: Ouellette, Andre J.; Tang, Yi-Quan; Selsted, Michael E.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to an isolated cyclic peptide theta defensin, having antimicrobial activity and to theta defensin analogs. A theta defensin can have the amino acid sequence Xaal-Xaa2-Xaa3-Xaa4-Xaa5-Xaa1-Xaa6-Xaa4-Xaa4- Xaa1-Xaa1-Xaa6-Xaa4-Xaa5-Xaa1-Xaa3-Xaa7-Xaa8 wherein Xaa1 to Xaa8 are , defined; wherein Xaa1 can be linked through a peptide bond to Xaa8; and wherein crosslinks can be formed between Xaa3 and Xaa3 between Xaa5 and Xaa5, and between Xaa7 and Xaa7. For example the invention provides a theta , defensin having the amino acid sequence Gly-Phe-Cys-Arg-Cys-Leu- Cys-Arg-Arg- Gly-Val-Cys-Arg-Cys-Ile-Cys-Thr-Arg (SEQ ID NO:1) wherein the Gly at position , 1 (Gly-1) is …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
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- Filed May 10, 2000 and granted July 8, 2014. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended May 10, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 10, 2022.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.