Ecotine derivatives
CA 2369027 A1 · Owner: Lundblad, Roger L. · Inventors: Lundblad, Roger L.; Fletterick, Robert J.; Craik, Charles S.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
This invention provides a class binding proteins that specifically bind to and modulate (e.g. enhance) the activity of polypeptides having a chymotrypsin fold (e.g. serine proteases). The binding proteins are based on the structure of ecotin. It was discovered that modification of the amino or carboxyl terminus and/or randomization of one or more of loops 50s 60s, 80s or 100s , will provide an ecotin variant library from which can be selected binding molecules (e.g. protease modulators) specific to virtually any serine protease. Depending on the ecotin variant and the target serine protease the , modulator can act as a serine protease inhibitor or as a serine protease activator. …
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 12, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended April 12, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 12, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.