N-(2-phenyl-4-amino-butyl)-1-naphthamides as neurokinin-1 receptor antagonists
CA 2368240 A1 · Owner: Bernstein, Peter Robert · Inventors: Bernstein, Peter Robert
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A compound having the general formula (I): R1R2N-CH2CH2-CHAr1-CH2-NR3-CO-R4 wherein: R1 is hydrogen, C1-6 alkyl, C2-6 alkenyl aryl, C1-6 alkanoyl C1-6 , alkoxycarbonyl or arylcarbonyl; any of such groups being optionally substituted; R2 is hydrogen or C1-6 alkyl; or R1 or R2 are joined to form an optionally substituted morpholino ring; Ar1 is phenyl mono- or di-substituted by halo; R3 is hydrogen or C1-6 alkyl; R4 is optionally substituted naphth-1yl; or pharmaceutically acceptable salts thereof. These compounds antagonize the pharmacological actions of the endogenous neuropeptide tachykinins particularly the neurokinin 1 (NK1) receptor.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 3, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended April 3, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 3, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.