Method for producing glyco-conjugates of 20(s)-camptothecin
CA 2366632 A1 · Owner: Lerchen, Hans-Georg · Inventors: Lerchen, Hans-Georg
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to a method for producing glyco-conjugates of 20(S)camptothecin in which a 3-O-methylated .beta.-L-fucose building block is linked to the 20 hydroxyl group of a camptothecin derivative via thioureamodified peptide spacers, whereby the decisive step exists in the linking of the building block (II) with the building block (V) in the presence of a particular coupling reagent such as N-(dimethylamino)-1H-1,2,3-triazolo4,5bpyridin-1-yl-methylene-N-methylmethane-aminium hexafluorophosphate-N-oxide (HATU).
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed February 23, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended February 23, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by February 23, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.