Microbiological production method for .alpha.-l-aspartyl-l-phenylalanine
CA 2365594 A1 · Owner: Sonke, Theodorus · Inventors: Sonke, Theodorus; Marahiel, Mohamed Abdalla; Doekel, Sasha
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to a new microbiological method for the , production of .alpha.-L-aspartyl-L-phenylalanine (Asp-Phe) from the substrates L-aspartic acid (L-Asp) and L-phenylalanine (L-Phe) wherein the substrates are contacted, in the presence of ATP, with a non-ribosomal dipeptide synthetase comprising two minimal modules connected by one condensation domain wherein the N- resp. C-terminal modules are recognising L-Asp and L-Phe respectively, and the latter module is covalently bound at its N- terminal end to the condensation domain, and wherein each of these minimal modules is composed of an adenylation domain and a 4'-phosphopantetheinyl cofactor containing thiolation …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 28, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended March 28, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 28, 2022.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.