Centrifugally-enhanced method of determining ligand/target affinity
CA 2365300 A1 · Owner: Solomon, Larry R. · Inventors: Solomon, Larry R.; Egan, David A.; Harlan, John E.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Centrifugation is used to induce and/or enhance binding between macromolecular targets and either small-molecule ligands or larger biomolecules as single entities or mixtures. With the enhanced binding the method of the invention , permits detection of ligands that bind to target substances and improve the design of ligands. The process relies on centrifugal force to establish a differential and selective concentration gradient between macromolecular therapeutic targets and the desired ligands. Once formed the information , about the self-sorting binding events is derived by analyzing the differential gradient of macromolecules and ligands in situ or by fractionating the gradient …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 1, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended March 1, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 1, 2022.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.