An in vivo and in vitro model for cutaneous photoaging and oxidative damage
CA 2362585 A1 · Owner: Charles River Laboratories, Inc. · Inventors: Bernstein, Eric F.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Transgenic hairless mice which express a full length or truncated human elastin promoter and fibroblast cultures derived from these transgenic mice are provided. Also provided are methods of identifying compounds capable of inhibiting cutaneous photodamage with these transgenic hairless mice or fibroblast cultures derived from these mice. In addition an in vitro system , for identifying agents capable of inhibiting or preventing oxidative damage in these mice fibroblast culture wherein reactive oxygen species are generated within the mouse fibroblast culture and a method for identifying agents which prevent oxidative damage are provided.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed February 22, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended February 22, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by February 22, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.