Improved helper dependent vector system for gene therapy
CA 2360796 A1 · Owner: Youil, Rima · Inventors: Youil, Rima; Bett, Andrew; Sandig, Volker
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention features helper-dependent adenoviral vector elements and helper adenoviral elements, that enhance the production and isolation of helper-dependent adenoviral vectors. Such elements include a modified packaging signal having low homology to and preferably less activity than, a , wild-type packaging signal an E4 non-coding segment directly joined to the 5' ITR that confers a selective advantage and stuffer region(s) that provide a , helper-dependent adenoviral vector with a GC content of about 50 % to about 60 %. The modified packaging signal is preferably used in a helper virus to decrease recombination and generation of the virus. The E4 non-coding segment and …
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 31, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended January 31, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 31, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.