Determining protein function and interaction from genome analysis
CA 2359898 A1 · Owner: Grothe, Robert · Inventors: Marcotte, Edward; Thompson, Michael; Eisenberg, David
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A computational method system, and computer program are provided for inferring functional links from genome sequences. One method is based on the observation that some pairs of proteins A' and B' have homologs in another organism fused into a single protein chain AB. A trans-genome comparison of sequences can reveal these AB sequences, which are Rosetta Stone sequences because they decipher an interaction between A' and B. Another method compares the genomic sequence of two or more organisms to create a phylogenetic profile for each protein indicating its presence or absence across all the genomes. The profile provides information regarding functional links between different …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 28, 2000. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended January 28, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 28, 2022.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.