Assay for identifying modulators of chondrogenesis
CA 2357549 A1 · Owner: Underhill, Tully Michael · Inventors: Underhill, Tully Michael; Weston, Andrea Dawn
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A screening assay for identifying modulators of chondrogenesis is described. The assay comprises providing cells capable of differentiating into chondroblasts; transfecting the cells with a nucleic acid construct comprising a, reporter gene that is detectable upon chondroblast differentiation; adding a test compound to the transfected cells; and determining the effect of the test compound on chondroblast differentiation. The reporter gene is preferably responsive to the transcription factor Sox9. The modulators may be useful as therapeutic agents that can inhibit or enhance cartilage formation. The assay may also be used to diagnose, monitor or prognose diseases associated with abnormal …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 21, 2001. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended September 21, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 21, 2023.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.