Generation of transgenic mouse models for the development of prostate cancer using regulatory regions of the psp94 gene
CA 2357181 A1 · Owner: Chin, Joseph L. · Inventors: Xuan, Jim W.; Panchal, Chandra J.; Chin, Joseph L.
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Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The utility of the promoter/enhancer region (i.e. regulatory region) of the PSP94 gene in targeting expression of heterologous genes, to the prostate gland was analyzed. Three breeding lines (i.e. line A, line B line C) of the PSP-TGMAP (PSP94 gene driven transgenic mouse of adenocarcinoma of the prostate) model were established with constructs containing regulatory regions with or without additional exon/intron sequence of the PSP94 gene. These regulatory regions were operatively linked to the simian virus 40 (SV40) T antigen (Tag, including both the large T and small t antigens). Histopathology evaluation of tumor grade transgene, expression, tumor responsiveness to androgen deprivation …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
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- Filed August 31, 2001. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended August 31, 2021.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.