An animal model for identifying a common stem/progenitor to liver cells and pancreatic cells
CA 2355971 A1 · Owner: The Scripps Research Institute · Inventors: Sarvetnick, Nora; Krakowski, Michelle L.; Kritzik, Marcie R.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention provides animal models, where the ectopic expression of KGF EGF, or both is under the control of a pancreas-specific promoter e.g. the , insulin promoter. The expression of KGF in the ins-KGF pancreatic islets of Langerhans results in enlarged islets, with substantial proliferation of duct cells within the islet mass, and the presence of albumin and alpha-fetoproteinproducing hepatocytes in the islets of the ins-KGF pancreata. The compositions and methods disclosed are useful for identifying and isolating pancreatic stem/progenitor cells, including a common stem/progenitor to liver cells and pancreatic cells.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 13, 1999. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended December 13, 2019.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 13, 2021.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.