Tissue collection devices containing biosensors

Abstract From the Canadian patent

The present invention provides tissue collection devices particularly blood , collection devices comprising an electrode. The electrodes may further comprise self-assembled monolayers and capture binding ligands particularly , nucleic acid capture probes. The monolayers may comprise insulators and/or electroconduit-forming species (EFS). The devices may further comprise at least one reagent, including anticoagulants probe nucleic acids, and lysis , reagents. In a further aspect the invention provides methods of detecting a target analyte in a sample comprising applying an initiation signal to a tissue collection device comprising an electrode. The electrode may comprise a …