Reversible aqueous ph sensitive lipidizing reagents, compositions and methods of use
CA 2354142 A1 · Owner: Shen, Wei-Chiang · Inventors: Shen, Wei-Chiang; Heiati, Hashem
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides lipidized conjugates comprising an amino groupcontaining biologically active substance and a lipophilic group capable of penetrating a biological membrane. Under neutral or mildly acidic conditions including those found in vivo, the free amino group-containing biologically active substance is released from the conjugate by hydrolysis of an amide bond. The present invention is also directed to methods of preparing lipidizing agents and lipidized conjugates pharmaceutical compositions , comprising lipidized conjugates and methods of increasing the delivery of amino group-containing substances into a cell. Preferred amino groupcontaining substances include …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 9, 1999. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended December 9, 2019.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 9, 2021.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.