Amino- and mercurio-substituted 4',5'-dihydropsoralens and therapeutical uses thereof
CA 2352665 A1 · Owner: Heindel, Ned D. · Inventors: Heck, Diane E.; Heindel, Ned D.; Mcneel, Thomas E.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
5'- substituted, 4', 5'- dihydropsoralen compounds (5) bearing tertiary amines (and salts thereof), quaternary ammonium moieties or organomercurial moieties are described. Also described are 2- substituted mercurimethyl -2-3- dihydro benzofurans of formula (7). Also reported are versatile direct syntheses through a hitherto unknown compounds such as 3-R-4 8-dimethyl -4',5'-dihydro -, 5'-bromomethylpsoralen or a 3-R-4 8-dimethyl-4, 5'-dihydro- 5'-, iodomethylpsoralen to prepare a structurally diverse array of partially reduced psoralens and benzofurans. The presence of a permanent ammonium charge in these psoralens precludes membrane passage and the mono-unsaturation precludes the …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed November 24, 1999. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended November 24, 2019.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by November 24, 2021.
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.