Hydrophilic somatostatin analogs

Abstract From the Canadian patent

The invention features novel somatostatin analogs that may be readily labeled with toxic or non-toxic detectable labels. These unlabeled and labeled analogs are useful for specifically targeting somatostatin receptor bearing cells in , particular neoplatic cells. Labeled analogs are useful for example, for tumor , localization and detection. Where labeled with a toxic label (e.g. radioactivity) the analogs are useful for the targeted delivery of toxicity to somatostatin receptor-bearing cells in particular neoplastic cells. Also , disclosed are methods for treating and detecting neoplasms and methods for , imaging somatostatin receptor-bearing cells.