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Delivery of superoxide dismutase to neuronal cells

CA 2349496 A1 · Owner: Silman, Nigel · Inventors: Hallis, Bassam; Silman, Nigel; Shone, Clifford Charles

CIPO record

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Abstract From the Canadian patent

A composition for delivery of superoxide dismutase to neuronal cells comprise a superoxide dismutase linked by a linker to a neuronal cell targeting component, which component comprises a first domain that binds to a neuronal cell and a second domain that translocates the superoxide dismutase into the neuronal cell. After translocation, the linker is cleaved to release superoxide dismutase from the neuronal cell targeting domain. Also described is use of the composition for treatment of oxidative damage to neuronal cells and further targeting of the composition using human mitochondrial leader sequences. A hybrid polypeptide is described that contains a bacterial superoxide …

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed November 5, 1999. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended November 5, 2019.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by November 5, 2021.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledNovember 5, 1999
GrantedNo grant recorded
Term endedNovember 5, 2019
Patent numberCA 2349496 A1
Classification (IPC)C12N15/53 +2 more

Timeline

Timeline From CIPO dates

2000200220042006200820102012201420162018Application filedNov 5, 1999Term endedNov 5, 2019

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.