Protective recombinant haemophilus influenzae high molecular weight proteins
CA 2345208 C · Owner: Connaught Laboratories Limited · Inventors: Klein, Michel H.; Yang, Yan-Ping; Loosmore, Sheena M.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Protective high molecular weight (HMW) proteins are produced recombinantly by expression from E. coli by using a promoter effective in E. coli and a nucleic acid molecule which contains a modified operon of a non-typeable strain of Haemophilus. The modified operon contains the portion only of the A region which encodes the mature HMW protein and the complete B and C regions of the operon. Enhanced levels of expression of the HMW proteins can be achieved by including the E. coli cer gene, a further copy of the portion of the A region of the operon encoding the mature protein or both in the expression vector. , Nucleotide and deduced amino acid sequences of the hmw1 and hmw2 genes and …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed October 7, 1999 and granted January 17, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended October 7, 2019.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by October 7, 2021.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.