Expression vectors containing hot spot for increased recombinant protein expression in transfected cells
CA 2344699 A1 · Owner: Bristol-Myers Squibb Company · Inventors: Koduri, Kanakaraju; Thammana, Pallaiah; Miller, John T.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A specific locus (hot spot) for recombinant gene expression has been identified in the genome of Chinese hamster ovary cells. A DNA vector containing the hot spot causes high levels of recombinant gene expression following transfection and stable integration. The selection and cloning of the specific locus and the expression of recombinant genes is disclosed as , are the DNA vectors and the host cells.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 7, 1999. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended September 7, 2019.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 7, 2021.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.