Control of cell growth by altering cell membrane potentials
CA 2343455 A1 · Owner: Minuk, Gerald Y. · Inventors: Minuk, Gerald Y.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Gamma aminobutyric acid (GABA) is a potent inhibitory neurotransmitter that binds to hetero-oligomeric receptors in the mammalian brain. In, a previous study, we documented specific GABA binding to isolated rat hepatocytes, which resulted in inhibition of hepatocyte proliferation. The purpose of the present, study was to define the nature of hepatic GABA A receptors and document their expression during rapid liver growth (post-partial hepatectomy). Polymerase chain, reactions (PCR) with gene-specific primers derived from published sequences were, performed with marathon-ready human and rat liver cDNA. Two GABA A receptor subunit types (.beta.3 and .epsilon.) were expressed in the human …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 30, 2001. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended March 30, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 30, 2023.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.