Modifying protein immunogenicity
CA 2342967 A1 · Owner: Adair, Fiona Suzanne · Inventors: Carr, Francis Joseph; Hamilton, Anita Anne; Adair, Fiona Suzanne
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
It is known that proteins, or parts of them may be rendered non- or less , immunogenic to humans or other species by identifying one or more potential T cell epitopes and eliminating them by amino acid modification. Conventionally certain epitopes may be retained in a protein sequence if the peptides constituting such epitopes are present in endogenous human protein since they , would be recognised as "self". However it has now been found that even self , epitopes may give rise to immune reactions. The invention provides for their elimination, for example by recombinant DNA technology to render them more , useful for administration to humans for example for therapeutic or diagnostic …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 8, 1999. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended December 8, 2019.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 8, 2021.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.