Improved process for the preparation of salts and esters of clavulanic acid
CA 2337072 A1 · Owner: Kerkhof, Pieter Theodorus · Inventors: Lefferts, Ageeth Geertruida; Kerkhof, Pieter Theodorus
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A process for the production of an amine salt of clavulanic acid and the conversion thereof into a pharmaceutically acceptable salt or ester thereof has been provided. During the crystallisation phase of the amine salt of clavulanic acid either a clavulanic acid containing solution optionally with , a cosolvent, is added to the amine or both reactants are added together to a cristallisation vessel. Also the application of a temperature profile (decreasing in time), profile of speed of addition (increasing in time) and a profile of the ratio amine/clavulanic acid (increasing in time) for this cristallisation process has been provided for.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 13, 1999. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended July 13, 2019.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 13, 2021.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.