Reducing background in hybridisation reactions
CA 2332729 A1 · Owner: Primagen Holding B.V. · Inventors: De Baar, Marinus Petrus; Timmermans, Eveline Catherina Anna Clasina; Van Gemen, Bob
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention provides a method for reducing background in hybridisation reactions of nucleic acids involving at least two homologous probes, wherein at least one of said probes is non-linear, or two homologous target sequences and a non-linear probe. Background is reduced by introducing an intended mismatch with a target sequence in at least one of said probes. The presence of the mismatch reduces the specificity of probes not entirely complementary to a target sequence to such an extent that the background signal is reduced. A set of mixed homologous probes, wherein at least one of said probes is non-linear, comprising such specific mismatch is also provided. Said set can be used for the …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed February 16, 2001. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended February 16, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by February 16, 2023.
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Timeline
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.