Methods for generating highly diverse libraries
CA 2331926 C · Owner: Adnexus, A Bristol-Myers Squibb R&D Company · Inventors: Kreider, Brent; Wagner, Richard; Wright, Martin C.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Disclosed herein is a method for generating a nucleic acid library the method , involving: (a) providing a population of single-stranded nucleic acid templates, each of the templates including a coding sequence and an operably linked promoter sequence; (b) hybridizing to the population of single-stranded nucleic acid templates a mixture of substantially complementary singlestranded nucleic acid fragments, the fragments being shorter in length than the nucleic acid template; (c) contacting each of the hybridization products of step (b) with both a DNA polymerase which lacks strand displacement activity and a DNA ligase under conditions in which the fragments act as primers for the …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed June 29, 1999 and granted September 10, 2013. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended June 29, 2019.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by June 29, 2021.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.