Method for the production of conjugates and uses thereof for the prevention and treatment of allergic reactions and autoimmune diseases
CA 2331012 A1 · Owner: Gelfand, Erwin · Inventors: Schelgel, Werner; Gelfand, Erwin; Borel, Yves
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to a method for the preparation of a conjugate comprising a first and a second polypeptide said method comprising the steps , of, (a) incubating said first polypeptide in the presence of a heterobifunctional crosslinker comprising an N-hydroxylsuccinimide ester group and a maleimide group linked via a polyethylene oxide spacer; (b) removing excess heterobifunctional crosslinker; and (c) incubating the reaction product of step (b), with said second polypeptide wherein said second polypeptide comprises at least, one sulfhydryl group. Furthermore the present invention relates to a conjugate obtainable by the method, of the present invention. Also described is a …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 10, 2001. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended January 10, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 10, 2023.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.