Amino-modified ribozymes
CA 2329247 A1 · Owner: Sioud, Mouldy · Inventors: Sioud, Mouldy
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to ribozymes modified to improve their stability methods for producing such enzymes and the use of the modified enzymes in methods such as therapeutic treatment. In particular a typical ribozyme , according to the invention includes a modified ribozyme wherein three or more , pyrimidine nucleotides in said ribozyme are modified at the 2'-position wherein said pyrimidine nucleotides are modified to 2'-amino pyrimidine nucleotides and said ribozyme exhibits improved stability to RNAse degradation and exhibits 85 % or more catalytic activity of the unmodified ribozyme.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 28, 1999. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 28, 2019.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 28, 2021.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.